The limo, which was bringing guests to a wedding, failed to stop at an intersection, and sailed into the parking lot of a nearby Apple Barrel, where it struck an unoccupied auto and two pedestrians, police confirm.
Police said everyone inside the limousine, including the driver, died in the crash, and all those killed were adults.
The New York-based news service added that the limousine was carrying a wedding party before the deadly crash.
Twenty people were killed when a limousine crashed into a crowd of bystanders outside a country store in upstate NY.
Authorities plan to hold a press conference on the crash at 3 p.m. ET on Sunday.
Photos from Times-Union photographer Peter R. Barber showed a white van-style stretch limousine lodged in a ditch, along with police and emergency vehicles that had converged upon the scene.
"They were wonderful girls", said their aunt, Barbara Douglas, speaking with reporters Sunday.
The limousine had been speeding downhill before the crash. A few have left bouquets of flowers wrapped in colored cellophane at the edge of the ditch, others make the sign of the cross and say a prayer. It really is. It's an incredible number of people for a community this small. "There's just a lot of confusion, so many people died", he said. Board Chairman Robert Sumwalt said it was the biggest US transportation accident since 2009.
When she got out of her vehicle, she saw a body on the ground and broken tree branches everywhere, she said.
New York State Police is not releasing the identities of those killed until officials notify next of kin. "There have been tractor trailers that have come barreling down that hill and it was a miracle they didn't kill somebody", said Tavenner, the paper reported.
On Saturday afternoon in the rural town of Schoharie, about 40 miles west of Albany, a 2001 Ford Excursion limousine failed to stop at the intersection of New York State Routes 30 and 30A. Chairman Robert Sumwalt said the crash was "the most deadly transportation accident in this country since February 2009", when a plane crashed into a house outside Buffalo, New York, killing 49 people.
The state police were assisted at the scene by the Schoharie County Sheriff's Office and numerous first-responders.
The Apple Barrell store appeared to address the crash in a Sunday morning Facebook post. He directed state agencies to provide "every resource necessary" to aid in New York's investigation.