The victor will clinch the division title, a spot in the National League Division Series and home-field advantage throughout the playoffs, while the loser will play in the NL Wild Game Game on Tuesday night.
For the first time in history, MLB's regular season will conclude with two different tiebreakers, a thrilling conclusion to a topsy-turvy year across the National League.
In the first game of Monday's unprecedented doubleheader, the Milwaukee Brewers will meet the Chicago Cubs at Wrigley Field at 1 p.m. ET. The Dodgers jumped on the Giants for seven runs in the third inning en route to a 15-0 win.
Wild-card games on Tuesday (losers of Brewers-Cubs and Rockies-Dodgers games) and Wednesday (Athletics at Yankees) will narrow the field to eight teams, four in each league, as the chase begins in earnest for the World Series crown.
The Rockies scored two in the first and added a pair in the third and just kept on scoring in a 12-0 win over the Nationals.
The Brewers finish their 162-games slate against the Detroit Tigers Sunday afternoon, while the Cubs will take on the St. Louis Cardinals in a practically parallel timeframe (2:10 p.m CT and 2:20 p.m CT first pitches respectively).
Yelich has 109 RBIs, tied with Colorado's Nolan Arenado and two behind leader Javier Baez of the Cubs.
The victor celebrates a National League Central title and prepares to open the playoffs on Thursday as a No. 1 seed.
Jose Quintana (13-11, 4.09 ERA) is expected to start for Chicago, while Milwaukee's starter hasn't been announced.