Hazard has been regularly linked with a move to FC Barcelona's bitter rivals Real Madrid over the past three or four seasons but a deal has failed to materlaise.
He will also be hoping to take the lead later this year in his personal race with Barcelona forward Lionel Messi for most Ballon d'Or awards, although fans will now have fewer on-field battles between the two to enjoy.
Ronaldo also won the Champions League with Manchester United in 2008 before departing for Real in a then-world record £80m one year later.
According to Madrid-based paper Marca, the club have a superstar-filled list of alternatives to fill the Portuguese's sizable boots - chief among those being Tottenham's Harry Kane. Their economic commitment represents far more than that, given that Ronaldo will draw a salary of some €30m a year in Turin.
I think it's a big challenge for him but he's going to a huge club.
"These years at Real Madrid and in this city of Real Madrid have quite possibly been the happiest years of my life".
Which is why the letter that Cristiano wrote to his fans, published on the Real Madrid fan site (here in English), is so well done. During these nine exciting years I have come up against great players.
EA Sports will have to change all of its covers and marketing materials to reflect the change of club by having Ronaldo in a Juventus shirt so it doesn't look outdated.
Kane plays in a similar position as Ronaldo, and would theoretically make more sense than Hazard, who is more of a playmaker and an attacking midfielder.
"These nine years have been absolutely marvellous".
No matter who comes to the attack, though, it will be a tough task to even get close to Ronaldo's success with Madrid.