TMZ has reported, Samantha is recovering in hospital after suffering what appears to be a broken ankle and a fractured knee.
Samantha's boyfriend told the outlet that he was driving in Ocala, Florida, when a paparazzi veered in front of them.
Mark says he swerved the vehicle to avoid the photographers but hit a concrete barrier, causing Samantha to hit the car's windshield before falling to the floor.
Just days prior to the her and Prince Harry's Royal wedding, Meghan Markle's half-sister Samantha Markle is refusing to be muzzled after her sister requested that she remains hush to the media amidst the tons of family drama.
Kensington Palace, which had previously confirmed Thomas would walk Meghan down the aisle, then released a statement saying: "This is a deeply personal moment for Ms Markle in the days before her wedding".
Meghan's sister, who suffers from multiple sclerosis, reportedly twisted her foot during the accident. She's way out of her league to tell me that I can't speak.
The alleged incident came after Samantha gave interviews on United Kingdom television about her half-sister's upcoming wedding to Prince Harry. Markle then reached out to him to her express her love and concern for him, putting him back in conversation for the ceremony.
Hopefully, Meghan Markle can get excited about this next bit of news despite the ongoing drama from her family.
Samantha, who revealed she had bought a wedding gift despite not being invited, said her relationship with Meghan was "strained".
Days later, he changed his tune and said he meant to walk his daughter down the aisle, but his plans were thwarted as a result of the heart surgery he underwent on Wednesday morning. But her mother, Doria Ragland, will be there!
Prince Harry and Markle are tying the knot on Saturday at St. George's Chapel at Windsor Castle.