Compared with controls, those with varicose veins had more incident DVT (6.55 per 1,000 person-years vs. 1.23 per 1,000 person-years; absolute risk difference, 5.32; 95% CI, 5.18-5.46) and significantly elevated risk for DVT (HR = 5.3; 95% CI, 5.05-5.56), according to the researchers.
The observational study analysed 212,984 people with varicose veins and 212,984 without and found that those with varicose veins were more likely to develop deep-vein thrombosis than those without.
They also found a higher incidence of pulmonary embolisms (PE) and peripheral artery disease (PAT) in people with varicose veins but the associations were less clear due to potential confounding factors.
Varicose veins are not just a cosmetic concern. They can be cause by aging, as veins lose elasticity over the years, causing the valves to weaken, Tech Times reports.
Varicose veins are veins that have become enlarged and twisted, most commonly appearing in the legs and feet.
They began with the thought "that varicose veins might be causal", he said.
The study used claims data from the Taiwanese National Health Insurance program linked to the National Register of Deaths, to propensity-score match 212,984 patients diagnosed with varicose veins to a paired control group.
Though they considered the health records of over 425,000 adults, the researchers say that even more work is needed to understand whether this relationship is one in which varicose veins directly cause blood clots or whether the two conditions simply have a similar origin.
Compared with the other adults, then, the varicose vein patients had slightly less than twice the risk of developing either condition.
"Not much is known about varicose veins and the risk of other vascular diseases", Chang said.
In any case, the new examination, by researchers in Taiwan, proposes it ought to be viewed as a notice sign that somebody is in danger of more significant issues.