Real moved four points above Valencia in third place, and manager Zinedine Zidane will be pleased to have had both Ronaldo and Gareth Bale on the scoresheet before Tuesday's trip to Paris to play a Neymar-less PSG. Messi needed 334 to reach the same mark.
However, our visitors did get a foot-hold back in the game when they were awarded a penalty kick after Nacho was adjudged to have fouled Jorge Molina inside the area.
Real came into the tie having suffered a 1-0 loss to Espanyol on Tuesday. "We played a very serious game".
"Before a second-leg game like Tuesday it was very important to have three days in a good mood", Zidane told reporters after the game.
Emerging for the second-half, any chances Getafe had of getting back into the game effectively ended when they were reduced to ten-men when Loic Remy was shown two yellow cards and a subsequent red-card. He nearly had a second late on but a curling shot nipped the post.
Tuesday's trip to the Parc des Princes will be Zidane's first return to France as a coach. But, on a night when his 117th La Liga appearance saw him pass David Beckham as the division's most capped British player, Bale delivered a timely reminder of his quality.
Madrid midfielders Luka Modric and Toni Kroos were again absent from training on Friday due to a knee and hamstring injury respectively, increasing concerns they will not be fit for the second leg in the French capital. It was Ramos who challenged with Isco for Benzema's deep cross in the 24th minute and as the ball dropped invitingly eight yards out, Bale applied the finish.
It was no surprise when Ronaldo doubled their advantage on the stroke of half-time. Ronaldo dashed their hopes, however, in the 78th minute heading in Marcelo's cross at the near post.