"Be prepared for a widespread, heavy and wet snowfall that will create hard travel conditions across the region", the weather service said.
Rain, sleet, heavy snow, and freezing rain are all possible Friday night into Saturday morning.
Winter weather advisories were scheduled to take effect in much of West Virginia, with the exceptions of the Eastern Panhandle and southeastern West Virginia counties, late Friday afternoon or Friday night.
In case the prediction turns out to be true, being prepared is the best way to beat the snow.
Temperatures will remain chilly Friday under increasingly cloudy skies. From basements flooding in Revere to Boston's waterfront disappearing under a tidal surge, a forecast of heavy rain on top of the piles of snow is not a welcome one.
TONIGHT: Cloudy skies and rain showers develop, with a low temperature of 48 degrees. Rainfall during this period is expected to reach 1.5 to 2.5 inches, with some areas receiving higher amounts, up to approximately 4 inches.
Temperatures are expected to drop for the weekend after a northern cold front moved into the area early Thursday with winds of about 30 to 40 miles per hour, National Weather Service Meteorologist Eric Platt said.
Temperatures are expected to fall below freezing by 1 to 3 p.m. for Western New York, including Buffalo, Niagara Falls and Jamestown.
Sunday: Mostly sunny, with a high near 20 degrees.
High temperatures will be rise Monday into the 30s, with lows in the teens.
Sunday night, there is a 50 percent chance of snow after midnight, according to the weather service. Partly sunny, with a high near 34.
The storm will move out of the region by Saturday afternoon and that will set us up for a dry Patriots playoff game Saturday night.