The 38-year-old tech tycoon - whose hardball exploits as Facebook's first president were depicted in Aaron Sorkin's 2010 Hollywood flick "The Social Network" - said Facebook is created to exploit "a vulnerability in human psychology" to get its users addicted.
There have been "unintended consequences", Parker said, now that Facebook has grown to include 2 billion people - two out of every seven people on the planet.
"It literally changes your relationship with society, with each other", Parker said, according to Axios. "God only knows what it's doing to our children's brains", said Parker.
Parker claimed that with the development of Facebook and other platforms, "the thought process was all about how to we consume as much of your time and conscious attention as possible". From there, he said that the system of "likes" was based upon giving users "a little dopamine hit" in the form of friendly approval.
Parker said that he and people like Zuckerberg realized they could keep their users engaged by "exploiting a vulnerability in human psychology" and creating 'a social-validation feedback loop'.
All people crave is appreciation and fame, and that's what social networks have given to the netizens.
Facebook has been attacked by one of its founding members for "exploiting a vulnerability in human psychology" and putting children's mental health at risk. "We'll get you eventually".
In an interview with Axios' Mike Allen, Parker, who was portrayed in the movie "The Social Network" by Justin Timberlake, said social networks have the power now to alter society and not for the better. Or Kevin Systrom, founder of Instagram, which Facebook owns.
Facebook didn't respond to a request for comment on Parker's remarks.
"As Parker left the stage, he joked that Mark Zuckerberg was going to block his Facebook account".
Now the founder and chair of the Parker Institute for Cancer Immunotherapy, Parker recently put $250 million of his money behind cancer research, making him the largest donor ever to immunotherapy treatment research. Yet "we did it anyway".
In a blog post, Facebook's chief security officer Alex Stamos wrote that "we will continue to invest in our people and technology to help provide a safe place for civic discourse and meaningful connections on Facebook".
When Facebook was getting going, I had these people who would come up to me and they would say, 'I'm not on social media.' And I would say, 'OK.