He said the incident appeared to be a targeted assassination attempt.
As a result of the explosion, one of the lawmaker's bodyguards and a passerby were killed, while Mosiychuk himself and three others suffered injuries and were taken to hospital.
One man was killed and four others injured in a blast in central Kiev, according to Ukraine's Interior Ministry.
A deadly detonation in Solomenskiy district of Kiev late on Wednesday has killed the security guard of the opposition Radical Party member Ihor Mosiychuk. "There is a lot of blood on the stairs, where Ihor was situated at the time of the explosion".
Ukrainian lawmaker Ihor Mosiychuk, who was known to insult Russian politicians, was wounded in a auto bomb.
Oleh Lyashko, the leader of the Radical Party, said the attack was "the work of our enemy's secret services".
According to the Ukrainian Police's statement, an explosive device was allegedly installed into the parked motorcycle and was remotely detonated, when Mosiychuk was near the entrance of the privately-owned TV Espresso channel.
Deputy Kyiv prosecutor Pavlo Kononenko said that Mosiychuk could have been targeted by Russian Federation, or by someone in Ukraine for political or personal reasons, Reuters reported. "Beyond all doubt", Dmitry Pescov told reporters, including the AP, "these are new signs of this anti-Russian campaign which has unfortunately swept across Ukraine and Kiev".
When the Chechen assassin, Artur Denisultanov-Kurmakayev, was interviewing the couple in a vehicle, he pulled out a gun and shot Osmayev.