Brussels had accused Google of giving more preference to its own services in the search results to the determinant of other price comparison sites, such as TripAdvisor and Expedia.
In June the EC judged that Google had given the service "an illegal advantage by abusing its dominance in general Internet search" - accusing it of promoting Google Shopping in organic search results while simultaneously demoting rival services - issuing a record-breaking €2.42 billion (~$2.73BN) fine for the antitrust violations.
If it did not, the Commission said, it faced penalty payments of up to 5 per cent of the average daily worldwide turnover of Alphabet, which is Google's parent company.
The company has submitted plans on how it plans to stop favouring its shopping service and these are now being reviewed by Brussels.
A court battle between Brussels and Google could take years to resolve and adds to an increasingly bitter row between the USA giant and European countries. A court spokeswoman said Google has not asked for an interim order to suspend the decision to levy an fine.
Last week, EU officials said a plan that Google recently filed to comply with European regulations appeared to be a step "in the right direction". Last week, Google also notified the European Union that it would attempt to meet the demands of the European Union decision.
The fine handed to Google was a significant hike on the previous record penalty of €1.06bn (£937m) dished out by the commission to U.S. microchip firm Intel in 2009.
European regulators are also expected to levy further fines in separate cases over Google's Android smartphone software and its AdSense advertising business as early as next month.