The Kabul peace conference comes amid an acute foreign relations crisis, as the majority of Afghans accuse Pakistan of continuing to host the Taliban leadership and its most murderous wing, the Haqqani group.
A bomb planted in a rickshaw killed at least seven people and wounded eight others in Herat city, an Afghan official. The Taliban already control or contest more than half of Afghanistan's populated areas, according to US estimates, making it harder for the U.S.to extract itself from its longest-ever war. However, this was their last chance, Ghani said.
Previous estimates said 90 people were killed in the bombing, the country's deadliest militant attack since 2001.
Also on the agenda are joint regional initiatives against terrorist organisations active in Afghanistan, such as al-Qaeda and Islamic State.
"The Kabul process aims to build an inclusive peace in Afghanistan, with the support of neighboring countries and the global community", he said. "We must stay strong and united". The worsening security situation necessitates cooperation between Afghan political forces, regional stakeholders and the worldwide community.
The Taliban made steady gains in the country since the worldwide military mission declared an end to its combat mission in 2014.
Meanwhile, the Taliban now control more than a third of the country.
Instead of blaming Pakistan, Afghanistan needs to look inward and identify the real issues, they said.
"This is something that the Afghans want to lead".
A spokesman for the Taliban told Reuters news agency he had no comment to make on the conference.
The Trump administration and military commanders are debating whether to send up to 5,000 more troops to stem the government's losses.
"The conference will be a visible reminder to all those who seek to harm Afghanistan that the Afghan people are never alone, especially in the wake of last week's attack", Llorens said in a statement.
"Afghans. It's always Afghans", she said, when asked who suffered in such attacks. "But whoever may be responsible for the latest spate of brutal attacks, the Afghan government would do better to focus on this growing threat rather than hurl baseless accusations against Pakistan", she had said.