"I want to call on Muslims and Christians to learn to pray for our leaders at all times, especially during their trying moments".
"He is our son and he needs our prayers and encouragement".
"I am sure that the medical vacation has refreshed him and made him ready for the tasks ahead".
He did not reveal the details of his condition, though, telling his listeners instead that he was "feeling much better now".
"We will continue to support him to succeed, " he said.
The Ahmed Makarfi faction of the Peoples Democratic Party (PDP) has urged the presidency to be more transparent in managing the health of President Muhammadu Buhari.
He said the president was back to continue with the task of repositioning Nigeria on the path of progress and development.
A civic group, CISLAC, had earlier commended the president for asking Mr. Osinbajo to act as president while he recovered.
Agba noted that Buhari's action portrayed the change that he promised Nigerians.
"He has also improved the fortunes of the exchange rate and curbed the activities of herdsmen; we want Buhari to build on that", he said.
"The PDP will continue to pray for the president; all Nigerians should do same".
The President also met with members of the Federal Executive Council (FEC).
The Nigerian leader's sightings in London were few and far between.
He said such an arrangement would guarantee the sustenance of "the economic progress we have witnessed under Osinbajo and give President Buhari room to "rest".
Adesina recalled that the president left the shores of the country on January 19 for a vacation, during which he was schedule to undergo routine medical check-ups.
Nigerians on social media-including Buhari's wife, Aisha-welcomed the president back.