However, Chelsea have responded in devastating fashion, racking up seven straight league wins, while Christian Eriken's opener for Spurs at Stamford Bridge ended a run of six consecutive Premier League clean sheets.
Chelsea are first, one point ahead of Liverpool and Manchester City.
Spurs record of 6 wins and 6 draws had them in fifth place, but a first win at Stamford Bridge in 26 years would see them into the final Champions League place.
That victory was Chelsea's seventh in a row in Premier League competition, with a productive surge carrying them to the top-flight summit.
Reports claimed Chelsea are preparing contract talks next week to push through a new deal for the 25-year-old, who had spent time on loan at Liverpool, Stoke City and West Ham United in successive seasons prior to his breakthrough under Conte. "They are both good", Hazard said when asked who Chelsea's main challengers are.
Souness admits the Reds will be disappointed to lose a key man at a crucial stage of the season, but hopes they can challenge for more than merely a top-four finish and push in-form Chelsea and the rest of the title hopefuls close in the battle for domestic dominance.
I don't want to jinx it, but we also seem to be dealing with our injury situation well, and are also expected to welcome back the likes of Lucas Perez, Danny Welbeck and Santi Cazorla in the coming weeks, which will only strengthen our options. "We have another type of confidence", Conte said.
Antonio Conte's side next travel to the Etihad Stadium where they face Manchester City on Saturday. They pushed us and supported us a lot during the game.
"You can win big matches even if you're not having a good season, because it is a big match or a derby, but it is the smaller matches against hard adversaries that you will see if you are going to be champions or not".
Chelsea's title credentials were widely questioned following back-to-back defeats against Liverpool and Chelsea in September, which saw the Blues fall eight points Pep Guardiola's men. "It's important to stay humble", Conte said.
It's been a frustrating few days for Spurs manager Mauricio Pochettino and his team, who were eliminated from the Champions League midweek at the hands of Monaco and on Saturday their winless streak at the Brdige was extended to 30 games. We are concentrating on the opposition during the week and give everything.
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