Apple jumped $6.36, or 6.6 percent, to $103.03. The S&P 500 lost 0.3% to 2168, while the NASDAQ eased 0.1% to 5098.
Traders have priced in an 18.7 percent chance of a rate increase in September and a 42.8 percent chance in December, according to CME Group's FedWatch tool. It was the first day of trading for the producer of natural gas and oil after it reported higher-than-expected earnings and raised its forecast for production this year.
The S&P 500 is down 8.45 points, or 0.4 percent.
The yield on the 30-year Treasury bond climbed to 2.30 percent from 2.29 percent.
ANALYST TAKE: "It wants to hike rates but can't; not while peers are moving in the opposite direction, their own currency-weakening action effectively delivering tighter US policy by sending the dollar higher", said Mike van Dulken, head of research at Accendo Markets. The social media company reported another loss and said user adoption rates continue to slow.
"It's really now becoming a question on whether Twitter as a concept is something financially viable", Morgan said.
The Federal Reserve voted to keep interest rates unchanged while noting that "near-term risks" to the economy have "diminished". Wait, a strong USA economy is pushing bond yields up, you say?
Other markets: Oil futures settled down 2.3% at $41.92 a barrel (http://www.marketwatch.com/story/oil-prices-stick-at-three-month-low-gasoline-inventories-are-a-problem-2016-07-27), their lowest level since mid-April, after data showed domestic crude products, notably gasoline, rose unexpectedly.
Oil prices continued to plumb new lows on Wednesday after U.S. government data showed a surprise build in crude and gasoline stockpiles. Marathon Oil, Transocean and Hess Corporation all fell roughly 4 percent or more. Brent crude, used to price global oils, fell $1.40 to $43.47 a barrel in London. For last few months, housing values there have risen by more than 10 percent year-over-year.
Boeing swung to a quarterly loss, but it wasn't as bad as analysts feared, and its shares rose 1.11, or 0.8%, to 135.96.
The West Texas Intermediate (WTI) benchmark for United States crude futures fell $1.09 or 2.5% to $41.83 a barrel, the lowest level on the New York Mercantile Exchange since April 19.